DESCRIPTION

Reacts with Canine Parvovirus CPV-2A and CPV-2B (does not react with CPV-1); also reacts with Feline Panleukopenia Virus and Mink Enteritis Virus IgG_2a isotype. This monoclonal antibody is produced as mouse ascites fluid, clarified by centrifugation, and filtered through a 0.2 micrometer filter. The concentration is 1.0 mg/ml in phosphate-buffered saline containing 4 mg/ml BSA, preserved with sodium azide.  Suitable for indirect immunofluorescence and virus neutralization.

REFERENCES

• Strassheim, M.L., et al. Two dominant neutralizing antigenic determinants of canine parvovirus are found on the threefold spike of the virus capsid. Virology 198(1):175-184 (Jan. 1994).
• Wikoff, W.R., et al. The structure of a neutralized virus: Canine parvovirus complexed with neutralizing antibody fragment. Structure 2(7):595-607 (July 1994).
• Ramos-Vara, J.A., and M.E. Beissenherz. Optimization of immunohistochemical methods using two different antigen retrieval methods on formalin-fixed paraffin-embedded tissues: Experience with 63 markers. J. Vet. Diagn. Invest. 12(4):307-311 (July 2000).